METHODS AND COMPOSITIONS FOR DETECTING AND PROMOTING CARDIOLIPIN REMODELING AND CARDIOMYOCYTE MATURATION AND RELATED METHODS OF TREATING MITOCHONDRIAL DYSFUNCTION

Embodiments of the disclosure relate to methods and compositions for inducing maturation of cardiomyocytes. In some embodiments, the cardiomyocytes are derived from stem cells, in vitro. In some embodiments, the compositions and methods induce maturation by inducing overexpression of a Let7i microRN...

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Bibliographische Detailangaben
Hauptverfasser:	Miklas, Jason Wayne, Wang, Yuliang, Ruohola-Baker, Hannele
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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