IMMUNOTHERAPY OF SOLID TUMORS BY VACCINATION WITH TRANSGENIC LEISHMANIA EXPRESSING CANCER VACCINES AND WITH RECOMBINANT VACCINES WITH LEISHMANIA AS ADJUVANTS

IMMUNOTHERAPY OF SOLID TUMORS BY VACCINATION WITH TRANSGENIC LEISHMANIA EXPRESSING CANCER VACCINES AND WITH RECOMBINANT VACCINES WITH LEISHMANIA AS ADJUVANTS

Disclosed herein are methods of vaccination against cancer by providing a sample of a photo-inactivated Leishmania optionally transgenically modified to express a cancer antigen such as alpha-enolase; optionally providing an effective amount of an alpha-enolase; and delivering an effective amount of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kolli, Bala K, Chang, Kwang-Poo
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed herein are methods of vaccination against cancer by providing a sample of a photo-inactivated Leishmania optionally transgenically modified to express a cancer antigen such as alpha-enolase; optionally providing an effective amount of an alpha-enolase; and delivering an effective amount of the sample and/or the alpha-enolase to a patient in need thereof.