ANTI-TRANSTHYRETIN ANTIBODIES

The invention provides antibodies that specifically bind to transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for dia...

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Hauptverfasser: SALMANS, Joshua Reginald, BARBOUR, Robin, ALEXANDER, Svetlana, HIGAKI, Jeffrey N, NIJJAR, Tarlochan S
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creator SALMANS, Joshua Reginald
BARBOUR, Robin
ALEXANDER, Svetlana
HIGAKI, Jeffrey N
NIJJAR, Tarlochan S
description The invention provides antibodies that specifically bind to transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for diagnosing TTR amyloidosis and inhibiting or reducing aggregation of TTR, and for monitoring the efficacy of TTR therapies, among other applications.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title ANTI-TRANSTHYRETIN ANTIBODIES
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