INTENSITY MODULATED PROTON THERAPY (IMPT) PLAN OPTIMIZATION BASED AT LEAST ON INTERNAL ORGAN ANTICIPATED MOVEMENT AND/OR EXPECTED DEFORMATION

INTENSITY MODULATED PROTON THERAPY (IMPT) PLAN OPTIMIZATION BASED AT LEAST ON INTERNAL ORGAN ANTICIPATED MOVEMENT AND/OR EXPECTED DEFORMATION

A method includes generating a nominal dose distribution based on an image and clinical goals. The method further includes generating a setup error dose distribution based on range and setup uncertainties. The method further includes generating a dose distribution for a parameter of an internal orga...

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Hauptverfasser: KUMAR, Ajesh, JOE ANTO, Gipson, RANGANATHAN, Vaitheeswaran
Format: Patent
Sprache:eng
Schlagworte:
ELECTROTHERAPY
HUMAN NECESSITIES
HYGIENE
MAGNETOTHERAPY
MEDICAL OR VETERINARY SCIENCE
RADIATION THERAPY
ULTRASOUND THERAPY
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creator KUMAR, Ajesh
JOE ANTO, Gipson
RANGANATHAN, Vaitheeswaran
description A method includes generating a nominal dose distribution based on an image and clinical goals. The method further includes generating a setup error dose distribution based on range and setup uncertainties. The method further includes generating a dose distribution for a parameter of an internal organ. The method further includes optimizing a planned dose distribution of an intensity modulated proton therapy plan by minimizing a total objective value including the nominal dose distribution, the setup error dose distribution dose distribution, and the dose distribution for the internal organ. The method further includes generating a final dose distribution for the intensity modulated proton therapy plan based on beam parameters of the optimized planned dose distribution. The method further includes controlling a proton therapy apparatus configured to deliver proton therapy based on the intensity modulated proton therapy plan with the optimized planned dose distribution.
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subjects ELECTROTHERAPY
HUMAN NECESSITIES
HYGIENE
MAGNETOTHERAPY
MEDICAL OR VETERINARY SCIENCE
RADIATION THERAPY
ULTRASOUND THERAPY
title INTENSITY MODULATED PROTON THERAPY (IMPT) PLAN OPTIMIZATION BASED AT LEAST ON INTERNAL ORGAN ANTICIPATED MOVEMENT AND/OR EXPECTED DEFORMATION
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