Devices and Methods for Vascular Hyperperfusion of Extravascular Space

A method of delivering a therapeutic substance for treatment to a region of the body through vascular isolation and manipulation of fluid flux into and from the region of the body including the steps of: restricting vascular inflow to the region of the body; washing out oncotically active plasma pro...

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Bibliographische Detailangaben
Hauptverfasser: Khin, Nyan, Kyung, Chris, Huckson, Matthew James, Lane, Rodney James, Murphy, Scott, Lane, David
Format: Patent
Sprache:eng
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Zusammenfassung:A method of delivering a therapeutic substance for treatment to a region of the body through vascular isolation and manipulation of fluid flux into and from the region of the body including the steps of: restricting vascular inflow to the region of the body; washing out oncotically active plasma proteins from the region of the body by increasing the outward oncotic pressure gradient from the region of the body; inducing ischemia in the region of the body; controlling the pressure and fluid flow of the main blood vessels to and from the region of the body; providing the therapeutic substance to the region of the body when the fluid flow to the region of the body is controlled.