METHOD FOR PREPARING (R)-N-[4-(1-AMINO-ETHYL)-2,6-DIFLUORO-PHENYL]-METHANESULFONAMIDE

Disclosed in the present specification is a method capable of preparing N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]-methanesulfonamide (INT028-2) with high optical purity, through the selection of Ellman-chiral auxiliaries and the re-crystallization and separation...

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Bibliographische Detailangaben
Hauptverfasser: WOO, Byoung Young, RAMAMOHAN, M, REGATI, Sridhar, LEE, Jihae, JAYAPRAKASH, Sarva, PARK, Young-Ho, SRINIVAS, Mamidi, LEE, Ki-Wha, CHOI, Chang Soon, PARK, Miyoung, PATEL, Krushnakant
Format: Patent
Sprache:eng
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