INHIBITORS OF BETA SECRETASE

INHIBITORS OF BETA SECRETASE

wherein the radicals are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorde...

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Hauptverfasser: Van Brandt, Sven Franciscus Anna, Gijsen, Henricus Jacobus Maria, Vos, Ann Marleen, Oehlrich, Daniel
Format: Patent
Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator Van Brandt, Sven Franciscus Anna
Gijsen, Henricus Jacobus Maria
Vos, Ann Marleen
Oehlrich, Daniel
description wherein the radicals are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease, dementia associated with beta-amyloid, age-related macular degeneration, type 2 diabetes and other metabolic disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title INHIBITORS OF BETA SECRETASE
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