GIP DERIVATIVES AND USES THEREOF

The present invention relates to novel peptides that are derivatives of glucose-dependent insulinotropic polypeptide (GIP) analogues having improved physical stability in solution and a protracted profile of action. More particular the invention relates to such peptides that are agonists at the GIP...

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Hauptverfasser: Reedtz-Runge, Steffen, Liu, Fa, Thoegersen, Henning, Knerr, Patrick J, Lau, Jesper F, DiMarchi, Richard, Finan, Brian, Hogendorf, Wouter Frederik Johan, Cox, Nicholas Raymond
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creator Reedtz-Runge, Steffen
Liu, Fa
Thoegersen, Henning
Knerr, Patrick J
Lau, Jesper F
DiMarchi, Richard
Finan, Brian
Hogendorf, Wouter Frederik Johan
Cox, Nicholas Raymond
description The present invention relates to novel peptides that are derivatives of glucose-dependent insulinotropic polypeptide (GIP) analogues having improved physical stability in solution and a protracted profile of action. More particular the invention relates to such peptides that are agonists at the GIP receptor and to their use in weight management or for treatment of diseases such as obesity, diabetes or non-alcoholic steatohepatitis (NASH).
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title GIP DERIVATIVES AND USES THEREOF
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