TUMOR SELECTIVE TATA-BOX AND CAAT-BOX MUTANTS

The invention provides, e.g., a recombinant virus comprising (i) a modified TATA box-based promoter, and/or (ii) a modified CAAT box-based promoter operably linked to a gene, wherein the modified TATA box-based promoter and/or modified CAAT box-based promoter lacks a functional TATA box and/or CAAT...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Oronsky, Bryan T, Hedjran, Farah, Reid, Tony R, Larson, Christopher
Format: Patent
Sprache:eng
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