ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reactio...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | GOULIAEV, Alex SAMS, Christian Klarner ANDERSEN, Anne Lee PEDERSEN, Henrik HOLTMANN, Anette FRESKGARD, Per-Ola NØRREGAARD-MADSEN, Mads GODSKESEN, Michael Anders OLSEN, Eva Kampmann KALDOR, Ditte Kievsmose HUSEMOEN, Gitte Nystrup FRANCH, Thomas PETERSEN, Lene THISTED, Thomas JENSEN, Kim Birkebæk FELDING, Jakob GLAD, Sanne Schrøder JAKOBSEN, Søren Nyboe GOLDBECH, Anne SØRENSEN, Anders Malling SLØK, Frank Abildgaard LUNDORF, Mikkel Dybro NEVE, Søren KRONBORG, Tine Titilola Akinleminu HANSEN, Anders Holm DOLBERG, Johannes de LEON, Daen |
| description | Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s). |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2019330618A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2019330618A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2019330618A13</originalsourceid><addsrcrecordid>eNrjZHB19YuK9HUM8XRWcPVz9nfx9HNX8HUN8fB3CVZw8w9ScHVz83T2dPULUQiO9AvxcA32DFbwd1PwcQxyd1Xw8XQKcgzydA3mYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBoaWxsYGZoYWjobGxKkCAEBQLQw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES</title><source>esp@cenet</source><creator>GOULIAEV, Alex ; SAMS, Christian Klarner ; ANDERSEN, Anne Lee ; PEDERSEN, Henrik ; HOLTMANN, Anette ; FRESKGARD, Per-Ola ; NØRREGAARD-MADSEN, Mads ; GODSKESEN, Michael Anders ; OLSEN, Eva Kampmann ; KALDOR, Ditte Kievsmose ; HUSEMOEN, Gitte Nystrup ; FRANCH, Thomas ; PETERSEN, Lene ; THISTED, Thomas ; JENSEN, Kim Birkebæk ; FELDING, Jakob ; GLAD, Sanne Schrøder ; JAKOBSEN, Søren Nyboe ; GOLDBECH, Anne ; SØRENSEN, Anders Malling ; SLØK, Frank Abildgaard ; LUNDORF, Mikkel Dybro ; NEVE, Søren ; KRONBORG, Tine Titilola Akinleminu ; HANSEN, Anders Holm ; DOLBERG, Johannes ; de LEON, Daen</creator><creatorcontrib>GOULIAEV, Alex ; SAMS, Christian Klarner ; ANDERSEN, Anne Lee ; PEDERSEN, Henrik ; HOLTMANN, Anette ; FRESKGARD, Per-Ola ; NØRREGAARD-MADSEN, Mads ; GODSKESEN, Michael Anders ; OLSEN, Eva Kampmann ; KALDOR, Ditte Kievsmose ; HUSEMOEN, Gitte Nystrup ; FRANCH, Thomas ; PETERSEN, Lene ; THISTED, Thomas ; JENSEN, Kim Birkebæk ; FELDING, Jakob ; GLAD, Sanne Schrøder ; JAKOBSEN, Søren Nyboe ; GOLDBECH, Anne ; SØRENSEN, Anders Malling ; SLØK, Frank Abildgaard ; LUNDORF, Mikkel Dybro ; NEVE, Søren ; KRONBORG, Tine Titilola Akinleminu ; HANSEN, Anders Holm ; DOLBERG, Johannes ; de LEON, Daen</creatorcontrib><description>Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMBINATORIAL CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191031&DB=EPODOC&CC=US&NR=2019330618A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191031&DB=EPODOC&CC=US&NR=2019330618A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GOULIAEV, Alex</creatorcontrib><creatorcontrib>SAMS, Christian Klarner</creatorcontrib><creatorcontrib>ANDERSEN, Anne Lee</creatorcontrib><creatorcontrib>PEDERSEN, Henrik</creatorcontrib><creatorcontrib>HOLTMANN, Anette</creatorcontrib><creatorcontrib>FRESKGARD, Per-Ola</creatorcontrib><creatorcontrib>NØRREGAARD-MADSEN, Mads</creatorcontrib><creatorcontrib>GODSKESEN, Michael Anders</creatorcontrib><creatorcontrib>OLSEN, Eva Kampmann</creatorcontrib><creatorcontrib>KALDOR, Ditte Kievsmose</creatorcontrib><creatorcontrib>HUSEMOEN, Gitte Nystrup</creatorcontrib><creatorcontrib>FRANCH, Thomas</creatorcontrib><creatorcontrib>PETERSEN, Lene</creatorcontrib><creatorcontrib>THISTED, Thomas</creatorcontrib><creatorcontrib>JENSEN, Kim Birkebæk</creatorcontrib><creatorcontrib>FELDING, Jakob</creatorcontrib><creatorcontrib>GLAD, Sanne Schrøder</creatorcontrib><creatorcontrib>JAKOBSEN, Søren Nyboe</creatorcontrib><creatorcontrib>GOLDBECH, Anne</creatorcontrib><creatorcontrib>SØRENSEN, Anders Malling</creatorcontrib><creatorcontrib>SLØK, Frank Abildgaard</creatorcontrib><creatorcontrib>LUNDORF, Mikkel Dybro</creatorcontrib><creatorcontrib>NEVE, Søren</creatorcontrib><creatorcontrib>KRONBORG, Tine Titilola Akinleminu</creatorcontrib><creatorcontrib>HANSEN, Anders Holm</creatorcontrib><creatorcontrib>DOLBERG, Johannes</creatorcontrib><creatorcontrib>de LEON, Daen</creatorcontrib><title>ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES</title><description>Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMBINATORIAL CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHB19YuK9HUM8XRWcPVz9nfx9HNX8HUN8fB3CVZw8w9ScHVz83T2dPULUQiO9AvxcA32DFbwd1PwcQxyd1Xw8XQKcgzydA3mYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBoaWxsYGZoYWjobGxKkCAEBQLQw</recordid><startdate>20191031</startdate><enddate>20191031</enddate><creator>GOULIAEV, Alex</creator><creator>SAMS, Christian Klarner</creator><creator>ANDERSEN, Anne Lee</creator><creator>PEDERSEN, Henrik</creator><creator>HOLTMANN, Anette</creator><creator>FRESKGARD, Per-Ola</creator><creator>NØRREGAARD-MADSEN, Mads</creator><creator>GODSKESEN, Michael Anders</creator><creator>OLSEN, Eva Kampmann</creator><creator>KALDOR, Ditte Kievsmose</creator><creator>HUSEMOEN, Gitte Nystrup</creator><creator>FRANCH, Thomas</creator><creator>PETERSEN, Lene</creator><creator>THISTED, Thomas</creator><creator>JENSEN, Kim Birkebæk</creator><creator>FELDING, Jakob</creator><creator>GLAD, Sanne Schrøder</creator><creator>JAKOBSEN, Søren Nyboe</creator><creator>GOLDBECH, Anne</creator><creator>SØRENSEN, Anders Malling</creator><creator>SLØK, Frank Abildgaard</creator><creator>LUNDORF, Mikkel Dybro</creator><creator>NEVE, Søren</creator><creator>KRONBORG, Tine Titilola Akinleminu</creator><creator>HANSEN, Anders Holm</creator><creator>DOLBERG, Johannes</creator><creator>de LEON, Daen</creator><scope>EVB</scope></search><sort><creationdate>20191031</creationdate><title>ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES</title><author>GOULIAEV, Alex ; SAMS, Christian Klarner ; ANDERSEN, Anne Lee ; PEDERSEN, Henrik ; HOLTMANN, Anette ; FRESKGARD, Per-Ola ; NØRREGAARD-MADSEN, Mads ; GODSKESEN, Michael Anders ; OLSEN, Eva Kampmann ; KALDOR, Ditte Kievsmose ; HUSEMOEN, Gitte Nystrup ; FRANCH, Thomas ; PETERSEN, Lene ; THISTED, Thomas ; JENSEN, Kim Birkebæk ; FELDING, Jakob ; GLAD, Sanne Schrøder ; JAKOBSEN, Søren Nyboe ; GOLDBECH, Anne ; SØRENSEN, Anders Malling ; SLØK, Frank Abildgaard ; LUNDORF, Mikkel Dybro ; NEVE, Søren ; KRONBORG, Tine Titilola Akinleminu ; HANSEN, Anders Holm ; DOLBERG, Johannes ; de LEON, Daen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2019330618A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2019</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMBINATORIAL CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>GOULIAEV, Alex</creatorcontrib><creatorcontrib>SAMS, Christian Klarner</creatorcontrib><creatorcontrib>ANDERSEN, Anne Lee</creatorcontrib><creatorcontrib>PEDERSEN, Henrik</creatorcontrib><creatorcontrib>HOLTMANN, Anette</creatorcontrib><creatorcontrib>FRESKGARD, Per-Ola</creatorcontrib><creatorcontrib>NØRREGAARD-MADSEN, Mads</creatorcontrib><creatorcontrib>GODSKESEN, Michael Anders</creatorcontrib><creatorcontrib>OLSEN, Eva Kampmann</creatorcontrib><creatorcontrib>KALDOR, Ditte Kievsmose</creatorcontrib><creatorcontrib>HUSEMOEN, Gitte Nystrup</creatorcontrib><creatorcontrib>FRANCH, Thomas</creatorcontrib><creatorcontrib>PETERSEN, Lene</creatorcontrib><creatorcontrib>THISTED, Thomas</creatorcontrib><creatorcontrib>JENSEN, Kim Birkebæk</creatorcontrib><creatorcontrib>FELDING, Jakob</creatorcontrib><creatorcontrib>GLAD, Sanne Schrøder</creatorcontrib><creatorcontrib>JAKOBSEN, Søren Nyboe</creatorcontrib><creatorcontrib>GOLDBECH, Anne</creatorcontrib><creatorcontrib>SØRENSEN, Anders Malling</creatorcontrib><creatorcontrib>SLØK, Frank Abildgaard</creatorcontrib><creatorcontrib>LUNDORF, Mikkel Dybro</creatorcontrib><creatorcontrib>NEVE, Søren</creatorcontrib><creatorcontrib>KRONBORG, Tine Titilola Akinleminu</creatorcontrib><creatorcontrib>HANSEN, Anders Holm</creatorcontrib><creatorcontrib>DOLBERG, Johannes</creatorcontrib><creatorcontrib>de LEON, Daen</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GOULIAEV, Alex</au><au>SAMS, Christian Klarner</au><au>ANDERSEN, Anne Lee</au><au>PEDERSEN, Henrik</au><au>HOLTMANN, Anette</au><au>FRESKGARD, Per-Ola</au><au>NØRREGAARD-MADSEN, Mads</au><au>GODSKESEN, Michael Anders</au><au>OLSEN, Eva Kampmann</au><au>KALDOR, Ditte Kievsmose</au><au>HUSEMOEN, Gitte Nystrup</au><au>FRANCH, Thomas</au><au>PETERSEN, Lene</au><au>THISTED, Thomas</au><au>JENSEN, Kim Birkebæk</au><au>FELDING, Jakob</au><au>GLAD, Sanne Schrøder</au><au>JAKOBSEN, Søren Nyboe</au><au>GOLDBECH, Anne</au><au>SØRENSEN, Anders Malling</au><au>SLØK, Frank Abildgaard</au><au>LUNDORF, Mikkel Dybro</au><au>NEVE, Søren</au><au>KRONBORG, Tine Titilola Akinleminu</au><au>HANSEN, Anders Holm</au><au>DOLBERG, Johannes</au><au>de LEON, Daen</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES</title><date>2019-10-31</date><risdate>2019</risdate><abstract>Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US2019330618A1 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T13%3A53%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GOULIAEV,%20Alex&rft.date=2019-10-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2019330618A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |