CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following stru...
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| creator | RAMSDEN, Philip Dean DRANSFIELD, Paul John YEH, Wen-Chen HOUZE, Jonathan MA, Zhihua LAI, Su-Jen HARVEY, James S KOPECKY, David J PATTAROPONG, Vatee HEATH, Julie Anne CHEN, Yinhong KHAKOO, Aarif Yusuf SWAMINATH, Gayathri NISHIMURA, Nobuko |
| description | Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures:(I) (II) where the definitions of the variables are provided herein. |
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Compounds of Formula I and Formula II have the following structures:(I) (II) where the definitions of the variables are provided herein.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190926&DB=EPODOC&CC=US&NR=2019290648A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190926&DB=EPODOC&CC=US&NR=2019290648A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RAMSDEN, Philip Dean</creatorcontrib><creatorcontrib>DRANSFIELD, Paul John</creatorcontrib><creatorcontrib>YEH, Wen-Chen</creatorcontrib><creatorcontrib>HOUZE, Jonathan</creatorcontrib><creatorcontrib>MA, Zhihua</creatorcontrib><creatorcontrib>LAI, Su-Jen</creatorcontrib><creatorcontrib>HARVEY, James S</creatorcontrib><creatorcontrib>KOPECKY, David J</creatorcontrib><creatorcontrib>PATTAROPONG, Vatee</creatorcontrib><creatorcontrib>HEATH, Julie Anne</creatorcontrib><creatorcontrib>CHEN, Yinhong</creatorcontrib><creatorcontrib>KHAKOO, Aarif Yusuf</creatorcontrib><creatorcontrib>SWAMINATH, Gayathri</creatorcontrib><creatorcontrib>NISHIMURA, Nobuko</creatorcontrib><title>CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR</title><description>Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures:(I) (II) where the definitions of the variables are provided herein.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPB0jnT28Xf08Y70UQgOdQoO8QwJDXF1UQgJ8nSM8vdxVXD29w3wD_VzCVZwBCJ3fz_P4JBgBX83hRAPVwXHAC-FIFdn14AQ_yAeBta0xJziVF4ozc2g7OYa4uyhm1qQH59aXJCYnJqXWhIfGmxkYGhpZGlgZmLhaGhMnCoAJfYugA</recordid><startdate>20190926</startdate><enddate>20190926</enddate><creator>RAMSDEN, Philip Dean</creator><creator>DRANSFIELD, Paul John</creator><creator>YEH, Wen-Chen</creator><creator>HOUZE, Jonathan</creator><creator>MA, Zhihua</creator><creator>LAI, Su-Jen</creator><creator>HARVEY, James S</creator><creator>KOPECKY, David J</creator><creator>PATTAROPONG, Vatee</creator><creator>HEATH, Julie Anne</creator><creator>CHEN, Yinhong</creator><creator>KHAKOO, Aarif Yusuf</creator><creator>SWAMINATH, Gayathri</creator><creator>NISHIMURA, Nobuko</creator><scope>EVB</scope></search><sort><creationdate>20190926</creationdate><title>CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR</title><author>RAMSDEN, Philip Dean ; DRANSFIELD, Paul John ; YEH, Wen-Chen ; HOUZE, Jonathan ; MA, Zhihua ; LAI, Su-Jen ; HARVEY, James S ; KOPECKY, David J ; PATTAROPONG, Vatee ; HEATH, Julie Anne ; CHEN, Yinhong ; KHAKOO, Aarif Yusuf ; SWAMINATH, Gayathri ; NISHIMURA, Nobuko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2019290648A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>RAMSDEN, Philip Dean</creatorcontrib><creatorcontrib>DRANSFIELD, Paul John</creatorcontrib><creatorcontrib>YEH, Wen-Chen</creatorcontrib><creatorcontrib>HOUZE, Jonathan</creatorcontrib><creatorcontrib>MA, Zhihua</creatorcontrib><creatorcontrib>LAI, Su-Jen</creatorcontrib><creatorcontrib>HARVEY, James S</creatorcontrib><creatorcontrib>KOPECKY, David J</creatorcontrib><creatorcontrib>PATTAROPONG, Vatee</creatorcontrib><creatorcontrib>HEATH, Julie Anne</creatorcontrib><creatorcontrib>CHEN, Yinhong</creatorcontrib><creatorcontrib>KHAKOO, Aarif Yusuf</creatorcontrib><creatorcontrib>SWAMINATH, Gayathri</creatorcontrib><creatorcontrib>NISHIMURA, Nobuko</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RAMSDEN, Philip Dean</au><au>DRANSFIELD, Paul John</au><au>YEH, Wen-Chen</au><au>HOUZE, Jonathan</au><au>MA, Zhihua</au><au>LAI, Su-Jen</au><au>HARVEY, James S</au><au>KOPECKY, David J</au><au>PATTAROPONG, Vatee</au><au>HEATH, Julie Anne</au><au>CHEN, Yinhong</au><au>KHAKOO, Aarif Yusuf</au><au>SWAMINATH, Gayathri</au><au>NISHIMURA, Nobuko</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR</title><date>2019-09-26</date><risdate>2019</risdate><abstract>Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures:(I) (II) where the definitions of the variables are provided herein.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR |
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