PROGRAMMABLE IMMUNOCYTE RECEPTOR COMPLEX SYSTEM

A programmable receptor complex expressed by an immunocyte, wherein the programmable receptor complex includes a plurality of native or endogenously-expressed receptor subunits, wherein at least one of the plurality of native or endogenously-expressed receptor subunits has been engineered or modifie...

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Bibliographische Detailangaben
Hauptverfasser: Tang, Yuanyuan, Kittle, Joseph D, Lwande, Joel S, Liang, Shengwen
Format: Patent
Sprache:eng
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Zusammenfassung:A programmable receptor complex expressed by an immunocyte, wherein the programmable receptor complex includes a plurality of native or endogenously-expressed receptor subunits, wherein at least one of the plurality of native or endogenously-expressed receptor subunits has been engineered or modified to include an FcγRI receptor component or a biotin-binding component, and wherein the FcγRI receptor component or biotin-binding component is operative to bind to a target detector molecule that binds to or otherwise interacts with a predetermined target.