Cyclic Peptides As C5a Receptor Antagonists

Cyclic Peptides As C5a Receptor Antagonists

The invention relates to cyclic peptide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to cyclic peptide C5a receptor antagonists of formula (Ia)or formula...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hepworth, David, Hayward, Matthew Merrill, Papaioannou, Nikolaos, Jones, Peter, Neelu, Kaila, Che, Ye, Feng, Yiqing
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Hepworth, David
Hayward, Matthew Merrill
Papaioannou, Nikolaos
Jones, Peter
Neelu, Kaila
Che, Ye
Feng, Yiqing
description The invention relates to cyclic peptide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to cyclic peptide C5a receptor antagonists of formula (Ia)or formula (Ib), or pharmaceutically acceptable salts thereof,wherein R1a, R1b, R2, R3 and R4 areas defined in the description. C5a receptor antagonists are potentially useful in the treatment of a wide range of 1 disorders,including inflammatory disorders and immune disorders.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2019270778A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2019270778A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2019270778A13</originalsourceid><addsrcrecordid>eNrjZNB2rkzOyUxWCEgtKMlMSS1WcCxWcDZNVAhKTQaK5BcpOOaVJKbn52UWlxTzMLCmJeYUp_JCaW4GZTfXEGcP3dSC_PjU4oLE5NS81JL40GAjA0NLI3MDc3MLR0Nj4lQBAKr-Ka0</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Cyclic Peptides As C5a Receptor Antagonists</title><source>esp@cenet</source><creator>Hepworth, David ; Hayward, Matthew Merrill ; Papaioannou, Nikolaos ; Jones, Peter ; Neelu, Kaila ; Che, Ye ; Feng, Yiqing</creator><creatorcontrib>Hepworth, David ; Hayward, Matthew Merrill ; Papaioannou, Nikolaos ; Jones, Peter ; Neelu, Kaila ; Che, Ye ; Feng, Yiqing</creatorcontrib><description>The invention relates to cyclic peptide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to cyclic peptide C5a receptor antagonists of formula (Ia)or formula (Ib), or pharmaceutically acceptable salts thereof,wherein R1a, R1b, R2, R3 and R4 areas defined in the description. C5a receptor antagonists are potentially useful in the treatment of a wide range of 1 disorders,including inflammatory disorders and immune disorders.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20190905&amp;DB=EPODOC&amp;CC=US&amp;NR=2019270778A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20190905&amp;DB=EPODOC&amp;CC=US&amp;NR=2019270778A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Hepworth, David</creatorcontrib><creatorcontrib>Hayward, Matthew Merrill</creatorcontrib><creatorcontrib>Papaioannou, Nikolaos</creatorcontrib><creatorcontrib>Jones, Peter</creatorcontrib><creatorcontrib>Neelu, Kaila</creatorcontrib><creatorcontrib>Che, Ye</creatorcontrib><creatorcontrib>Feng, Yiqing</creatorcontrib><title>Cyclic Peptides As C5a Receptor Antagonists</title><description>The invention relates to cyclic peptide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to cyclic peptide C5a receptor antagonists of formula (Ia)or formula (Ib), or pharmaceutically acceptable salts thereof,wherein R1a, R1b, R2, R3 and R4 areas defined in the description. C5a receptor antagonists are potentially useful in the treatment of a wide range of 1 disorders,including inflammatory disorders and immune disorders.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB2rkzOyUxWCEgtKMlMSS1WcCxWcDZNVAhKTQaK5BcpOOaVJKbn52UWlxTzMLCmJeYUp_JCaW4GZTfXEGcP3dSC_PjU4oLE5NS81JL40GAjA0NLI3MDc3MLR0Nj4lQBAKr-Ka0</recordid><startdate>20190905</startdate><enddate>20190905</enddate><creator>Hepworth, David</creator><creator>Hayward, Matthew Merrill</creator><creator>Papaioannou, Nikolaos</creator><creator>Jones, Peter</creator><creator>Neelu, Kaila</creator><creator>Che, Ye</creator><creator>Feng, Yiqing</creator><scope>EVB</scope></search><sort><creationdate>20190905</creationdate><title>Cyclic Peptides As C5a Receptor Antagonists</title><author>Hepworth, David ; Hayward, Matthew Merrill ; Papaioannou, Nikolaos ; Jones, Peter ; Neelu, Kaila ; Che, Ye ; Feng, Yiqing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2019270778A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Hepworth, David</creatorcontrib><creatorcontrib>Hayward, Matthew Merrill</creatorcontrib><creatorcontrib>Papaioannou, Nikolaos</creatorcontrib><creatorcontrib>Jones, Peter</creatorcontrib><creatorcontrib>Neelu, Kaila</creatorcontrib><creatorcontrib>Che, Ye</creatorcontrib><creatorcontrib>Feng, Yiqing</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Hepworth, David</au><au>Hayward, Matthew Merrill</au><au>Papaioannou, Nikolaos</au><au>Jones, Peter</au><au>Neelu, Kaila</au><au>Che, Ye</au><au>Feng, Yiqing</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Cyclic Peptides As C5a Receptor Antagonists</title><date>2019-09-05</date><risdate>2019</risdate><abstract>The invention relates to cyclic peptide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to cyclic peptide C5a receptor antagonists of formula (Ia)or formula (Ib), or pharmaceutically acceptable salts thereof,wherein R1a, R1b, R2, R3 and R4 areas defined in the description. C5a receptor antagonists are potentially useful in the treatment of a wide range of 1 disorders,including inflammatory disorders and immune disorders.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2019270778A1
source esp@cenet
subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Cyclic Peptides As C5a Receptor Antagonists
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T13%3A02%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Hepworth,%20David&rft.date=2019-09-05&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2019270778A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true