IL-6 BINDING MOLECULES
The present invention provides binding molecules (e.g., antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL-6 (e.g., human, mouse and non-human primate IL-6). In a preferred embodiment, the antibodies or antigen binding fragments of th...
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| creator | DE JONGE, Natalie VAN DER WONING, Sebastian Paul ONGENAE, Nicolas BLANCHETOT, Christophe DE HAARD, Johannes DREIER, Torsten |
| description | The present invention provides binding molecules (e.g., antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL-6 (e.g., human, mouse and non-human primate IL-6). In a preferred embodiment, the antibodies or antigen binding fragments of the invention bind to IL-6 and inhibit its binding to an IL-6 receptor. Such antibodies or antigen binding fragments are particularly useful for treating IL-6-associated diseases or disorders (e.g., inflammatory disease and cancer). |
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In a preferred embodiment, the antibodies or antigen binding fragments of the invention bind to IL-6 and inhibit its binding to an IL-6 receptor. Such antibodies or antigen binding fragments are particularly useful for treating IL-6-associated diseases or disorders (e.g., inflammatory disease and cancer).</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190801&DB=EPODOC&CC=US&NR=2019233509A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190801&DB=EPODOC&CC=US&NR=2019233509A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DE JONGE, Natalie</creatorcontrib><creatorcontrib>VAN DER WONING, Sebastian Paul</creatorcontrib><creatorcontrib>ONGENAE, Nicolas</creatorcontrib><creatorcontrib>BLANCHETOT, Christophe</creatorcontrib><creatorcontrib>DE HAARD, Johannes</creatorcontrib><creatorcontrib>DREIER, Torsten</creatorcontrib><title>IL-6 BINDING MOLECULES</title><description>The present invention provides binding molecules (e.g., antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL-6 (e.g., human, mouse and non-human primate IL-6). 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Such antibodies or antigen binding fragments are particularly useful for treating IL-6-associated diseases or disorders (e.g., inflammatory disease and cancer).</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBDz9NE1U3Dy9HPx9HNX8PX3cXUO9XEN5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8aHBRgaGlkbGxqYGlo6GxsSpAgASeh_R</recordid><startdate>20190801</startdate><enddate>20190801</enddate><creator>DE JONGE, Natalie</creator><creator>VAN DER WONING, Sebastian Paul</creator><creator>ONGENAE, Nicolas</creator><creator>BLANCHETOT, Christophe</creator><creator>DE HAARD, Johannes</creator><creator>DREIER, Torsten</creator><scope>EVB</scope></search><sort><creationdate>20190801</creationdate><title>IL-6 BINDING MOLECULES</title><author>DE JONGE, Natalie ; VAN DER WONING, Sebastian Paul ; ONGENAE, Nicolas ; BLANCHETOT, Christophe ; DE HAARD, Johannes ; DREIER, Torsten</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2019233509A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>DE JONGE, Natalie</creatorcontrib><creatorcontrib>VAN DER WONING, Sebastian Paul</creatorcontrib><creatorcontrib>ONGENAE, Nicolas</creatorcontrib><creatorcontrib>BLANCHETOT, Christophe</creatorcontrib><creatorcontrib>DE HAARD, Johannes</creatorcontrib><creatorcontrib>DREIER, Torsten</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DE JONGE, Natalie</au><au>VAN DER WONING, Sebastian Paul</au><au>ONGENAE, Nicolas</au><au>BLANCHETOT, Christophe</au><au>DE HAARD, Johannes</au><au>DREIER, Torsten</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IL-6 BINDING MOLECULES</title><date>2019-08-01</date><risdate>2019</risdate><abstract>The present invention provides binding molecules (e.g., antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL-6 (e.g., human, mouse and non-human primate IL-6). 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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | IL-6 BINDING MOLECULES |
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