METHOD FOR SYNTHESIZING NOVEL CHIRAL LIGAND, METAL CHELATE, A VARIETY OF NON-NATURAL AMINO ACIDS, MARAVIROC AND KEY INTERMEDIATE THEREOF

Disclosed is a method for synthesizing a novel chiral ligand, a metal chelate, a variety of non-natural amino acids, Maraviroc and a key intermediate thereof. In the invention, (R)-2-methyl proline is selected and used as a starting raw material, (S)-β3-amino acid is obtained by asymmetric resolutio...

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Hauptverfasser: NIAN, Yong, SHU, Shuangjie, PENG, Panfeng, WANG, Shuni, ZHOU, Shengbin, CHEN, Kaixian, LIU, Hong, JIANG, Hualiang, SHEN, Hao, WANG, Jiang
Format: Patent
Sprache:eng
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