METHODS OF PURIFYING AND QUALIFYING ANTIBODIES

A method of purifying a recombinant antibody having the complementarity determining regions (CDRs) of denosumab, the method comprising subjecting a preparation comprising said antibody to a mixed mode chromatography on a Capto™ Adhere column in a pH range of 6.2-7.4, thereby purifying the antibody....

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Bibliographische Detailangaben
1. Verfasser:	MIRON, Daphna
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS SEPARATION TESTING TRANSPORTING
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Beschreibung
Zusammenfassung:	A method of purifying a recombinant antibody having the complementarity determining regions (CDRs) of denosumab, the method comprising subjecting a preparation comprising said antibody to a mixed mode chromatography on a Capto™ Adhere column in a pH range of 6.2-7.4, thereby purifying the antibody.