METHOD AND APPARATUS FOR SUBRETINAL ADMINISTRATION OF THERAPEUTIC AGENT
An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is o...
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| creator | Oberkircher, Brendan J Khan, Isaac J Keane, Michael F Bruehwiler, Michel G Price, Daniel W Yasevac, Daniel J Grubbs, Nathan D Sokhanvar, Saeed Soffer, Leah R Riemann, Christopher D Ko, Benjamin L |
| description | An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy. |
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The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.</description><language>eng</language><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS ; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY ; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR ; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY ; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ; FILTERS IMPLANTABLE INTO BLOOD VESSELS ; FIRST-AID KITS ; FOMENTATION ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES ; PROSTHESES ; TREATMENT OR PROTECTION OF EYES OR EARS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190516&DB=EPODOC&CC=US&NR=2019142634A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25566,76549</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190516&DB=EPODOC&CC=US&NR=2019142634A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Oberkircher, Brendan J</creatorcontrib><creatorcontrib>Khan, Isaac J</creatorcontrib><creatorcontrib>Keane, Michael F</creatorcontrib><creatorcontrib>Bruehwiler, Michel G</creatorcontrib><creatorcontrib>Price, Daniel W</creatorcontrib><creatorcontrib>Yasevac, Daniel J</creatorcontrib><creatorcontrib>Grubbs, Nathan D</creatorcontrib><creatorcontrib>Sokhanvar, Saeed</creatorcontrib><creatorcontrib>Soffer, Leah R</creatorcontrib><creatorcontrib>Riemann, Christopher D</creatorcontrib><creatorcontrib>Ko, Benjamin L</creatorcontrib><title>METHOD AND APPARATUS FOR SUBRETINAL ADMINISTRATION OF THERAPEUTIC AGENT</title><description>An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. 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STENTS</subject><subject>FILTERS IMPLANTABLE INTO BLOOD VESSELS</subject><subject>FIRST-AID KITS</subject><subject>FOMENTATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</subject><subject>PROSTHESES</subject><subject>TREATMENT OR PROTECTION OF EYES OR EARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHD3dQ3x8HdRcPQD4oAAxyDHkNBgBTf_IIXgUKcg1xBPP0cfBUcXX08_z-AQoKSnv5-Cv5tCiIdrkGOAa2iIp7OCo7urXwgPA2taYk5xKi-U5mZQdnMNcfbQTS3Ij08tLkhMTs1LLYkPDTYyMLQ0NDEyMzZxNDQmThUAn8strw</recordid><startdate>20190516</startdate><enddate>20190516</enddate><creator>Oberkircher, Brendan J</creator><creator>Khan, Isaac J</creator><creator>Keane, Michael F</creator><creator>Bruehwiler, Michel G</creator><creator>Price, Daniel W</creator><creator>Yasevac, Daniel J</creator><creator>Grubbs, Nathan D</creator><creator>Sokhanvar, Saeed</creator><creator>Soffer, Leah R</creator><creator>Riemann, Christopher D</creator><creator>Ko, Benjamin L</creator><scope>EVB</scope></search><sort><creationdate>20190516</creationdate><title>METHOD AND APPARATUS FOR SUBRETINAL ADMINISTRATION OF THERAPEUTIC AGENT</title><author>Oberkircher, Brendan J ; Khan, Isaac J ; Keane, Michael F ; Bruehwiler, Michel G ; Price, Daniel W ; Yasevac, Daniel J ; Grubbs, Nathan D ; Sokhanvar, Saeed ; Soffer, Leah R ; Riemann, Christopher D ; Ko, Benjamin L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2019142634A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2019</creationdate><topic>BANDAGES, DRESSINGS OR ABSORBENT PADS</topic><topic>DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY</topic><topic>DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR</topic><topic>DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY</topic><topic>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PROSTHESES</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>Oberkircher, Brendan J</creatorcontrib><creatorcontrib>Khan, Isaac J</creatorcontrib><creatorcontrib>Keane, Michael F</creatorcontrib><creatorcontrib>Bruehwiler, Michel G</creatorcontrib><creatorcontrib>Price, Daniel W</creatorcontrib><creatorcontrib>Yasevac, Daniel J</creatorcontrib><creatorcontrib>Grubbs, Nathan D</creatorcontrib><creatorcontrib>Sokhanvar, Saeed</creatorcontrib><creatorcontrib>Soffer, Leah R</creatorcontrib><creatorcontrib>Riemann, Christopher D</creatorcontrib><creatorcontrib>Ko, Benjamin L</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Oberkircher, Brendan J</au><au>Khan, Isaac J</au><au>Keane, Michael F</au><au>Bruehwiler, Michel G</au><au>Price, Daniel W</au><au>Yasevac, Daniel J</au><au>Grubbs, Nathan D</au><au>Sokhanvar, Saeed</au><au>Soffer, Leah R</au><au>Riemann, Christopher D</au><au>Ko, Benjamin L</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD AND APPARATUS FOR SUBRETINAL ADMINISTRATION OF THERAPEUTIC AGENT</title><date>2019-05-16</date><risdate>2019</risdate><abstract>An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BANDAGES, DRESSINGS OR ABSORBENT PADS DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES TREATMENT OR PROTECTION OF EYES OR EARS |
| title | METHOD AND APPARATUS FOR SUBRETINAL ADMINISTRATION OF THERAPEUTIC AGENT |
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