Crystalline Form of Lumacaftor

The present invention provides a novel crystalline form of Lumacaftor, specifically Lumacaftor Form APO-1, a co-crystal of Lumacaftor and nicotinamide, compositions including this crystalline form, and processes for the preparation of this crystalline form.

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Bibliographische Detailangaben
Hauptverfasser: Khalili, Bahareh, Rantanen, Katherine A, Souza, Fabio E. S
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a novel crystalline form of Lumacaftor, specifically Lumacaftor Form APO-1, a co-crystal of Lumacaftor and nicotinamide, compositions including this crystalline form, and processes for the preparation of this crystalline form.