TRICYCLIC AND TETRACYCLIC SYSTEMS ACTING UPON THE VASCULAR AND CENTRAL NERVOUS SYSTEMS

Tricyclic and tetracyclic derivatives of benzodiazepine, pyridodiazepine, and pyrimidodiazepine fused with 1,4-dihydropyridine derivatives are disclosed. The present derivatives can be obtained from derivatives containing a dihydropyrldine ring reacting with compounds of the ortho-phenyldiamine, ort...

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Hauptverfasser: VERDECIA REYES, Yamila, RUIZ REYES, Alberto, CARILLO DOMÍNGUEZ, Carmen, TACORONTE MORALES, Juan Enrique, PARDO ANDREU, Gilberto Lázaro, OCHOA RODRÍGUEZ, Estael, ALBA GUTIÉRREZ, Livan Lázaro, NUÑEZ FIGUEREDO, Yanier
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creator VERDECIA REYES, Yamila
RUIZ REYES, Alberto
CARILLO DOMÍNGUEZ, Carmen
TACORONTE MORALES, Juan Enrique
PARDO ANDREU, Gilberto Lázaro
OCHOA RODRÍGUEZ, Estael
ALBA GUTIÉRREZ, Livan Lázaro
NUÑEZ FIGUEREDO, Yanier
description Tricyclic and tetracyclic derivatives of benzodiazepine, pyridodiazepine, and pyrimidodiazepine fused with 1,4-dihydropyridine derivatives are disclosed. The present derivatives can be obtained from derivatives containing a dihydropyrldine ring reacting with compounds of the ortho-phenyldiamine, ortho-diaminopyridine, and ortho-diaminopyrimidine type, as well as some subsequent transformations and, tricyclic and tetracyclic derivatives can be obtained with a diazepine or diazepinone nucleus fused to a 1,4-dihydropyridine nucleus, having a substituted or unsubstituted ring of benzene, pyridine or pyrimidine. The present derivatives exhibit vascular and central nervous system therapeutic activity.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title TRICYCLIC AND TETRACYCLIC SYSTEMS ACTING UPON THE VASCULAR AND CENTRAL NERVOUS SYSTEMS
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