RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER

RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER

The present invention provides compositions and methods for detection and analysis of intracellular binding of a bioactive agent to a cellular target. In particular, provided herein are bioactive agents tethered to fluorophores, cellular targets fused to bioluminescent reporters, and methods of dete...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Robers, Matt, Hitko, Carolyn W, Kirkland, Thomas, Ohana, Rachel Friedman, Machleidt, Thomas, Wood, Keith
Format: Patent
Sprache:eng
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Robers, Matt
Hitko, Carolyn W
Kirkland, Thomas
Ohana, Rachel Friedman
Machleidt, Thomas
Wood, Keith
description The present invention provides compositions and methods for detection and analysis of intracellular binding of a bioactive agent to a cellular target. In particular, provided herein are bioactive agents tethered to fluorophores, cellular targets fused to bioluminescent reporters, and methods of detecting and analyzing the interaction of bioactive agents with cellular targets therewith.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2019064192A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2019064192A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2019064192A13</originalsourceid><addsrcrecordid>eNqNizELwjAQhbs4iPofDpyFVkXoeI3XGIgXSC5Cp1IkTqKFuvjvbUGcnd57fN-bZ29Pymk2YhyDq0GRtdGiB0GvSaAyfDSsoWoAx-FQibkQoCYWiGFChsXj7zc6Np4NU1DEisBTcIxTIyavGxhlDjX5ZTa7dfchrb65yNY1iTptUv9s09B31_RIrzaGbV6U-WFflFssdv9ZH8SdO18</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER</title><source>esp@cenet</source><creator>Robers, Matt ; Hitko, Carolyn W ; Kirkland, Thomas ; Ohana, Rachel Friedman ; Machleidt, Thomas ; Wood, Keith</creator><creatorcontrib>Robers, Matt ; Hitko, Carolyn W ; Kirkland, Thomas ; Ohana, Rachel Friedman ; Machleidt, Thomas ; Wood, Keith</creatorcontrib><description>The present invention provides compositions and methods for detection and analysis of intracellular binding of a bioactive agent to a cellular target. In particular, provided herein are bioactive agents tethered to fluorophores, cellular targets fused to bioluminescent reporters, and methods of detecting and analyzing the interaction of bioactive agents with cellular targets therewith.</description><language>eng</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20190228&amp;DB=EPODOC&amp;CC=US&amp;NR=2019064192A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20190228&amp;DB=EPODOC&amp;CC=US&amp;NR=2019064192A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Robers, Matt</creatorcontrib><creatorcontrib>Hitko, Carolyn W</creatorcontrib><creatorcontrib>Kirkland, Thomas</creatorcontrib><creatorcontrib>Ohana, Rachel Friedman</creatorcontrib><creatorcontrib>Machleidt, Thomas</creatorcontrib><creatorcontrib>Wood, Keith</creatorcontrib><title>RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER</title><description>The present invention provides compositions and methods for detection and analysis of intracellular binding of a bioactive agent to a cellular target. In particular, provided herein are bioactive agents tethered to fluorophores, cellular targets fused to bioluminescent reporters, and methods of detecting and analyzing the interaction of bioactive agents with cellular targets therewith.</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNizELwjAQhbs4iPofDpyFVkXoeI3XGIgXSC5Cp1IkTqKFuvjvbUGcnd57fN-bZ29Pymk2YhyDq0GRtdGiB0GvSaAyfDSsoWoAx-FQibkQoCYWiGFChsXj7zc6Np4NU1DEisBTcIxTIyavGxhlDjX5ZTa7dfchrb65yNY1iTptUv9s09B31_RIrzaGbV6U-WFflFssdv9ZH8SdO18</recordid><startdate>20190228</startdate><enddate>20190228</enddate><creator>Robers, Matt</creator><creator>Hitko, Carolyn W</creator><creator>Kirkland, Thomas</creator><creator>Ohana, Rachel Friedman</creator><creator>Machleidt, Thomas</creator><creator>Wood, Keith</creator><scope>EVB</scope></search><sort><creationdate>20190228</creationdate><title>RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER</title><author>Robers, Matt ; Hitko, Carolyn W ; Kirkland, Thomas ; Ohana, Rachel Friedman ; Machleidt, Thomas ; Wood, Keith</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2019064192A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2019</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>Robers, Matt</creatorcontrib><creatorcontrib>Hitko, Carolyn W</creatorcontrib><creatorcontrib>Kirkland, Thomas</creatorcontrib><creatorcontrib>Ohana, Rachel Friedman</creatorcontrib><creatorcontrib>Machleidt, Thomas</creatorcontrib><creatorcontrib>Wood, Keith</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Robers, Matt</au><au>Hitko, Carolyn W</au><au>Kirkland, Thomas</au><au>Ohana, Rachel Friedman</au><au>Machleidt, Thomas</au><au>Wood, Keith</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER</title><date>2019-02-28</date><risdate>2019</risdate><abstract>The present invention provides compositions and methods for detection and analysis of intracellular binding of a bioactive agent to a cellular target. In particular, provided herein are bioactive agents tethered to fluorophores, cellular targets fused to bioluminescent reporters, and methods of detecting and analyzing the interaction of bioactive agents with cellular targets therewith.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2019064192A1
source esp@cenet
subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T14%3A46%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Robers,%20Matt&rft.date=2019-02-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2019064192A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true