ANTI-VEGFR ANTIBODY AND USES THEREOF
The present invention relates to an antibody or antigen-binding fragment thereof that bind human vascular endothelial growth factor receptor 2 (VEGFR-2). The present invention also relates to a method for inhibiting VEGFR-2-mediated signaling in a subject in need, a method for treating diseases and/...
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| creator | Hsu, Chuan-Lung Tsai, Yi-Jiue Lai, Yan-Da Tsai, Yi-San Wu, Yen-Yu Huang, Juo-Yu Wang, Li-Ya Ai, Li-Shuang Lai, Szu-Liang LAI, JIANN-SHIUN Yu, Cheng-Chou Kuan, Chien-Tsun |
| description | The present invention relates to an antibody or antigen-binding fragment thereof that bind human vascular endothelial growth factor receptor 2 (VEGFR-2). The present invention also relates to a method for inhibiting VEGFR-2-mediated signaling in a subject in need, a method for treating diseases and/or disorders caused by or related to VEGFR-2 activity and/or signaling in a subject afflicted with the diseases and disorders, a method for treating tumor in a subject afflicted with the tumor, a method for inhibiting cell proliferation of endothelial cells in a subject in need, and a method for detecting human vascular endothelial growth factor receptor in a sample. |
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The present invention also relates to a method for inhibiting VEGFR-2-mediated signaling in a subject in need, a method for treating diseases and/or disorders caused by or related to VEGFR-2 activity and/or signaling in a subject afflicted with the diseases and disorders, a method for treating tumor in a subject afflicted with the tumor, a method for inhibiting cell proliferation of endothelial cells in a subject in need, and a method for detecting human vascular endothelial growth factor receptor in a sample.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; TESTING</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180705&DB=EPODOC&CC=US&NR=2018186884A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180705&DB=EPODOC&CC=US&NR=2018186884A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Hsu, Chuan-Lung</creatorcontrib><creatorcontrib>Tsai, Yi-Jiue</creatorcontrib><creatorcontrib>Lai, Yan-Da</creatorcontrib><creatorcontrib>Tsai, Yi-San</creatorcontrib><creatorcontrib>Wu, Yen-Yu</creatorcontrib><creatorcontrib>Huang, Juo-Yu</creatorcontrib><creatorcontrib>Wang, Li-Ya</creatorcontrib><creatorcontrib>Ai, Li-Shuang</creatorcontrib><creatorcontrib>Lai, Szu-Liang</creatorcontrib><creatorcontrib>LAI, JIANN-SHIUN</creatorcontrib><creatorcontrib>Yu, Cheng-Chou</creatorcontrib><creatorcontrib>Kuan, Chien-Tsun</creatorcontrib><title>ANTI-VEGFR ANTIBODY AND USES THEREOF</title><description>The present invention relates to an antibody or antigen-binding fragment thereof that bind human vascular endothelial growth factor receptor 2 (VEGFR-2). 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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING |
| title | ANTI-VEGFR ANTIBODY AND USES THEREOF |
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