NK1 ANTAGONISTS
wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough....
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| creator | Paliwal Sunil Reichard Gregory A Palani Anandan Wrobleski Michelle Laci Xiao Dong Tsui Hon-Chung Arredondo Juan D Shih Neng-Yang Wang Cheng |
| description | wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed. |
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Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171005&DB=EPODOC&CC=US&NR=2017283434A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171005&DB=EPODOC&CC=US&NR=2017283434A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Paliwal Sunil</creatorcontrib><creatorcontrib>Reichard Gregory A</creatorcontrib><creatorcontrib>Palani Anandan</creatorcontrib><creatorcontrib>Wrobleski Michelle Laci</creatorcontrib><creatorcontrib>Xiao Dong</creatorcontrib><creatorcontrib>Tsui Hon-Chung</creatorcontrib><creatorcontrib>Arredondo Juan D</creatorcontrib><creatorcontrib>Shih Neng-Yang</creatorcontrib><creatorcontrib>Wang Cheng</creatorcontrib><title>NK1 ANTAGONISTS</title><description>wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOD38zZUcPQLcXT39_MMDgnmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBobmRhbGJsYmjobGxKkCAFYZHiM</recordid><startdate>20171005</startdate><enddate>20171005</enddate><creator>Paliwal Sunil</creator><creator>Reichard Gregory A</creator><creator>Palani Anandan</creator><creator>Wrobleski Michelle Laci</creator><creator>Xiao Dong</creator><creator>Tsui Hon-Chung</creator><creator>Arredondo Juan D</creator><creator>Shih Neng-Yang</creator><creator>Wang Cheng</creator><scope>EVB</scope></search><sort><creationdate>20171005</creationdate><title>NK1 ANTAGONISTS</title><author>Paliwal Sunil ; Reichard Gregory A ; Palani Anandan ; Wrobleski Michelle Laci ; Xiao Dong ; Tsui Hon-Chung ; Arredondo Juan D ; Shih Neng-Yang ; Wang Cheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2017283434A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Paliwal Sunil</creatorcontrib><creatorcontrib>Reichard Gregory A</creatorcontrib><creatorcontrib>Palani Anandan</creatorcontrib><creatorcontrib>Wrobleski Michelle Laci</creatorcontrib><creatorcontrib>Xiao Dong</creatorcontrib><creatorcontrib>Tsui Hon-Chung</creatorcontrib><creatorcontrib>Arredondo Juan D</creatorcontrib><creatorcontrib>Shih Neng-Yang</creatorcontrib><creatorcontrib>Wang Cheng</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Paliwal Sunil</au><au>Reichard Gregory A</au><au>Palani Anandan</au><au>Wrobleski Michelle Laci</au><au>Xiao Dong</au><au>Tsui Hon-Chung</au><au>Arredondo Juan D</au><au>Shih Neng-Yang</au><au>Wang Cheng</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NK1 ANTAGONISTS</title><date>2017-10-05</date><risdate>2017</risdate><abstract>wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NK1 ANTAGONISTS |
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