INHIBITORS OF HIF PROLYL HYDROXYLASE

INHIBITORS OF HIF PROLYL HYDROXYLASE

The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such...

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Hauptverfasser: LIU RONGQIANG, WANG LIPING, DUBOIS BYRON GABRIEL, LIU PING, SINZ CHRISTOPHER, CAI JIAQIANG, CRESPO ALEJANDRO, DU XIAOXING, QUAN WEIGUO
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Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator LIU RONGQIANG
WANG LIPING
DUBOIS BYRON GABRIEL
LIU PING
SINZ CHRISTOPHER
CAI JIAQIANG
CRESPO ALEJANDRO
DU XIAOXING
QUAN WEIGUO
description The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title INHIBITORS OF HIF PROLYL HYDROXYLASE
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