DUAL FUNCTION PROTEINS FOR TREATING METABOLIC DISORDERS

DUAL FUNCTION PROTEINS FOR TREATING METABOLIC DISORDERS

The present invention relates to the identification of new proteins comprising fibroblast growth factor 21 (FGF21) and other metabolic regulators, including variants thereof, known to improve metabolic profiles in subjects to whom they are administered. Also disclosed are methods for treating FGF21-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BOETTCHER Brian R, GEIERSTANGER Bernhard Hubert, LOEW Andreas, HAMAMATSU Norio, CAPLAN Shari Lynn, DANIELS Douglas S, CELLITTI Susan E, LICHT Stuart, WELDON Stephen Craig
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to the identification of new proteins comprising fibroblast growth factor 21 (FGF21) and other metabolic regulators, including variants thereof, known to improve metabolic profiles in subjects to whom they are administered. Also disclosed are methods for treating FGF21-associated disorders, GLP-1-associated disorders, and Exendin-4-associated disorders, including metabolic conditions.