DENGUE VIRUS VACCINE

Recombinant fusion proteins including a dengue virus EIII and an E2 subunit derived from a thermophilic bacterium are described. Also described are expression vectors including a polynucleotide that encodes the recombinant fusion protein and a promoter. Also described are vaccine compositions that i...

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Hauptverfasser: McBurney Sean P, Messer William, Haigwood Nancy
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creator McBurney Sean P
Messer William
Haigwood Nancy
description Recombinant fusion proteins including a dengue virus EIII and an E2 subunit derived from a thermophilic bacterium are described. Also described are expression vectors including a polynucleotide that encodes the recombinant fusion protein and a promoter. Also described are vaccine compositions that include either the recombinant fusion protein, polynucleotide, or both. Also described are methods of generating an immune response to dengue virus serotype 2 comprising administering one or more of the disclosed vaccine compositions.
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Also described are expression vectors including a polynucleotide that encodes the recombinant fusion protein and a promoter. Also described are vaccine compositions that include either the recombinant fusion protein, polynucleotide, or both. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title DENGUE VIRUS VACCINE
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