SEPARATION AND ASSAY OF TARGET ENTITIES USING FILTRATION MEMBRANES COMPRISING A PERFORATED TWO-DIMENSIONAL MATERIAL

Perforated graphene and other perforated two-dimensional materials can be used to sequester target entities having a particular range of sizes or chemical characteristics. The target entities sequestered thereon can be further assayed for quantification/qualification purposes. Use of multiple filter...

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Hauptverfasser: SIMON Sarah, STETSON John B
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STETSON John B
description Perforated graphene and other perforated two-dimensional materials can be used to sequester target entities having a particular range of sizes or chemical characteristics. The target entities sequestered thereon can be further assayed for quantification/qualification purposes. Use of multiple filter membranes can allow particular size ranges or chemical characteristics of target entities to be isolated and further analyzed. Methods for assaying a target entity, particularly a biological target entity, can include providing one or more filter membranes disposed in series with one another, the filter membranes containing a perforated two-dimensional material, and the filter membranes having an effective pore size that decreases in a direction of intended fluid flow; and passing a fluid through the filter membranes. The methods can also include assaying for at least one target entity on the filter membranes.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
SEPARATION
TESTING
TRANSPORTING
title SEPARATION AND ASSAY OF TARGET ENTITIES USING FILTRATION MEMBRANES COMPRISING A PERFORATED TWO-DIMENSIONAL MATERIAL
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