MULTI-INDICATION MRNA CANCER IMMUNOTHERAPY

MULTI-INDICATION MRNA CANCER IMMUNOTHERAPY

Synthetic bacterial messenger RNA can be used to prepare autologous, allogenic or direct nucleic acid cancer vaccines. Cancer cells are transfected either in vitro or in vivo with mRNA obtained from DNA that encodes an immunogenic bacterial protein. An immune response to the cancer is generated from...

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Hauptverfasser: LAWMAN PATRICIA D, RAMIYA VIJAY, LAWMAN MICHAEL J. P, GENTILINI MEGHAN, BASTAWROUS MARINA VICTOR ABDELMASEEH
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator LAWMAN PATRICIA D
RAMIYA VIJAY
LAWMAN MICHAEL J. P
GENTILINI MEGHAN
BASTAWROUS MARINA VICTOR ABDELMASEEH
description Synthetic bacterial messenger RNA can be used to prepare autologous, allogenic or direct nucleic acid cancer vaccines. Cancer cells are transfected either in vitro or in vivo with mRNA obtained from DNA that encodes an immunogenic bacterial protein. An immune response to the cancer is generated from direct administration of the mRNA in vivo or administration of vaccines prepared from cancer cells in vitro.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title MULTI-INDICATION MRNA CANCER IMMUNOTHERAPY
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