Drug Coated Balloon Catheter
The present invention relates to a drug coated balloon catheter, comprising a balloon and a drug coating covering the surface of the balloon; the drug coating comprises an active drug and a carrier; the active drug is paclitaxel, rapamycin, a paclitaxel derivative or rapamycin derivative; the carrie...
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| creator | XIE Qizong ZHANG Yongmu SONG Jingzhong LU Jinhua |
| description | The present invention relates to a drug coated balloon catheter, comprising a balloon and a drug coating covering the surface of the balloon; the drug coating comprises an active drug and a carrier; the active drug is paclitaxel, rapamycin, a paclitaxel derivative or rapamycin derivative; the carrier comprises an organic acid salt and polyalcohol; a mass ratio of the active drug to the carrier in the drug coating is 0.2 to 100, and a mass ratio of the organic acid salt to the polyalcohol is (0.2 to 5):1, The organic acid salt and the polyalcohol in the drug coating jointly take effect to prevent the premature release of drugs before the balloon catheter is positioned at a target site, and to promote the drugs being quickly released from the surface of the balloon and absorbed by the target tissue, thus reducing drug loss during transmission, and also having a better drug transfer effect. |
| format | Patent |
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the active drug is paclitaxel, rapamycin, a paclitaxel derivative or rapamycin derivative; the carrier comprises an organic acid salt and polyalcohol; a mass ratio of the active drug to the carrier in the drug coating is 0.2 to 100, and a mass ratio of the organic acid salt to the polyalcohol is (0.2 to 5):1, The organic acid salt and the polyalcohol in the drug coating jointly take effect to prevent the premature release of drugs before the balloon catheter is positioned at a target site, and to promote the drugs being quickly released from the surface of the balloon and absorbed by the target tissue, thus reducing drug loss during transmission, and also having a better drug transfer effect.</description><language>eng</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY ; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR ; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY ; 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the drug coating comprises an active drug and a carrier; the active drug is paclitaxel, rapamycin, a paclitaxel derivative or rapamycin derivative; the carrier comprises an organic acid salt and polyalcohol; a mass ratio of the active drug to the carrier in the drug coating is 0.2 to 100, and a mass ratio of the organic acid salt to the polyalcohol is (0.2 to 5):1, The organic acid salt and the polyalcohol in the drug coating jointly take effect to prevent the premature release of drugs before the balloon catheter is positioned at a target site, and to promote the drugs being quickly released from the surface of the balloon and absorbed by the target tissue, thus reducing drug loss during transmission, and also having a better drug transfer effect.</description><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY</subject><subject>DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR</subject><subject>DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJBxKSpNV3DOTyxJTVFwSszJyc_PU3BOLMlILUkt4mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8aHBRgaGZsbGhhbmBo6GxsSpAgD2aSQu</recordid><startdate>20161117</startdate><enddate>20161117</enddate><creator>XIE Qizong</creator><creator>ZHANG Yongmu</creator><creator>SONG Jingzhong</creator><creator>LU Jinhua</creator><scope>EVB</scope></search><sort><creationdate>20161117</creationdate><title>Drug Coated Balloon Catheter</title><author>XIE Qizong ; 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| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL |
| title | Drug Coated Balloon Catheter |
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