STEREO-SPECIFIC SYNTHESIS OF (13R)-MANOYL OXIDE
The present invention relates to a method for manufacturing enantiomerically pure (13R)-manoyl oxide, said method comprising the steps of contacting geranylgeranyl diphosphate (GGPP) with a class II diterpene synthase to obtain labd-13-en-8,15-diol diphosphate (LPP), and then contacting the LPP with...
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| creator | Pateraki Eirini Nielsen Morten Thrane NØRHOLM Morten Hamberger Björn Andersen-Ranberg Johan Bohlmann Carl Jörg Zerbe Phillipp Lindberg MØLLERø Birger |
| description | The present invention relates to a method for manufacturing enantiomerically pure (13R)-manoyl oxide, said method comprising the steps of contacting geranylgeranyl diphosphate (GGPP) with a class II diterpene synthase to obtain labd-13-en-8,15-diol diphosphate (LPP), and then contacting the LPP with a class I diterpene synthase to obtain (13R)-manoyl oxide. The invention further relates to (13R)-manoyl oxide obtained by the method of the invention. |
| format | Patent |
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The invention further relates to (13R)-manoyl oxide obtained by the method of the invention.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAPDnENcvXXDQ5wdfZ083RWCI70C_FwDfYMVvB3U9AwNA7S1PV19POP9FHwj_B0ceVhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfGhwUYGhmbGhhYWlsaOhsbEqQIAiEcmvQ</recordid><startdate>20161103</startdate><enddate>20161103</enddate><creator>Pateraki Eirini</creator><creator>Nielsen Morten Thrane</creator><creator>NØRHOLM Morten</creator><creator>Hamberger Björn</creator><creator>Andersen-Ranberg Johan</creator><creator>Bohlmann Carl Jörg</creator><creator>Zerbe Phillipp</creator><creator>Lindberg MØLLERø Birger</creator><scope>EVB</scope></search><sort><creationdate>20161103</creationdate><title>STEREO-SPECIFIC SYNTHESIS OF (13R)-MANOYL OXIDE</title><author>Pateraki Eirini ; Nielsen Morten Thrane ; NØRHOLM Morten ; Hamberger Björn ; Andersen-Ranberg Johan ; Bohlmann Carl Jörg ; Zerbe Phillipp ; Lindberg MØLLERø Birger</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2016318893A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2016</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Pateraki Eirini</creatorcontrib><creatorcontrib>Nielsen Morten Thrane</creatorcontrib><creatorcontrib>NØRHOLM Morten</creatorcontrib><creatorcontrib>Hamberger Björn</creatorcontrib><creatorcontrib>Andersen-Ranberg Johan</creatorcontrib><creatorcontrib>Bohlmann Carl Jörg</creatorcontrib><creatorcontrib>Zerbe Phillipp</creatorcontrib><creatorcontrib>Lindberg MØLLERø Birger</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Pateraki Eirini</au><au>Nielsen Morten Thrane</au><au>NØRHOLM Morten</au><au>Hamberger Björn</au><au>Andersen-Ranberg Johan</au><au>Bohlmann Carl Jörg</au><au>Zerbe Phillipp</au><au>Lindberg MØLLERø Birger</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>STEREO-SPECIFIC SYNTHESIS OF (13R)-MANOYL OXIDE</title><date>2016-11-03</date><risdate>2016</risdate><abstract>The present invention relates to a method for manufacturing enantiomerically pure (13R)-manoyl oxide, said method comprising the steps of contacting geranylgeranyl diphosphate (GGPP) with a class II diterpene synthase to obtain labd-13-en-8,15-diol diphosphate (LPP), and then contacting the LPP with a class I diterpene synthase to obtain (13R)-manoyl oxide. The invention further relates to (13R)-manoyl oxide obtained by the method of the invention.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | STEREO-SPECIFIC SYNTHESIS OF (13R)-MANOYL OXIDE |
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