EPITHELIAL-MESENCHYMAL TRANSITION IN CIRCULATING TUMOR CELLS (CTCS) NEGATIVES FOR CYTOKERATIN (CK) EXPRESSION IN PATIENTS WITH NON-METASTATIC BREAST CANCER

The inventors of the present invention have surprisingly discovered that EGFR expression in nonmetastatic breast cancer patients with CK-negative CTCs could induce EMT process. A simultaneous detection of both EGFR and EMT markers (VIM and Slug) in CTCs might improve prognostic or predictive informa...

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Hauptverfasser: GARCÍA PUCHE José Luis, SERRANO FERNÁNDEZ María José, LORENTE ACOSTA José Antonio, ORTEGA SÁNCHEZ Francisco Gabriel, MARCHAL CORRALES Juan Antonio
Format: Patent
Sprache:eng
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