RHO KINASE INHIBITORS
Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compos...
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| creator | Kirrane, JR. Thomas Martin Wu Frank Young Erick Richard Ginn John David Turner Michael Robert Bosanac Todd Snow Roger John Prokopowicz Anthony S Shih Cheng-Kon Schlyer Sabine K Liu Weimin Hickey Eugene Richard |
| description | Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds. |
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Thomas Martin</au><au>Wu Frank</au><au>Young Erick Richard</au><au>Ginn John David</au><au>Turner Michael Robert</au><au>Bosanac Todd</au><au>Snow Roger John</au><au>Prokopowicz Anthony S</au><au>Shih Cheng-Kon</au><au>Schlyer Sabine K</au><au>Liu Weimin</au><au>Hickey Eugene Richard</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RHO KINASE INHIBITORS</title><date>2016-08-25</date><risdate>2016</risdate><abstract>Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | RHO KINASE INHIBITORS |
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