Process for Preparation of Olanzapine Pamoate

Process for Preparation of Olanzapine Pamoate

An improved process for preparation of Olanzapine pamoate monohydrate from Olanzpaine is disclosed which comprises mixing at room temperature a solution of olanzapine prepared in water in presence of an acid, with a solution of pamoic acid prepared in water in presence of a base; stirring and mainta...

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Hauptverfasser: NEELA PRAVEENKUMAR, REDDY KUBIREDDY VIGNESHWAR, WADEKAR KASHYAP RAVINDRABHAI, LAXMALLA SAMPATH KUMAR, RAVI PONNAIAH
Format: Patent
Sprache:eng
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator NEELA PRAVEENKUMAR
REDDY KUBIREDDY VIGNESHWAR
WADEKAR KASHYAP RAVINDRABHAI
LAXMALLA SAMPATH KUMAR
RAVI PONNAIAH
description An improved process for preparation of Olanzapine pamoate monohydrate from Olanzpaine is disclosed which comprises mixing at room temperature a solution of olanzapine prepared in water in presence of an acid, with a solution of pamoic acid prepared in water in presence of a base; stirring and maintaining the reaction mixture for a sufficient time till precipitation of solid and drying the solid to obtain olazapine pamoate monohydrate.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Process for Preparation of Olanzapine Pamoate
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