FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS

Assay methods may generally comprise forming homogeneous assay mixtures comprising target SAM-utilizing protein, fluorescent detection analyte, and test compound, incubating, and measuring FP or TR-FRET signal emitted in order to determine a measure of test compound-SAM-utilizing protein binding. As...

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Hauptverfasser: CISKE FRED LAWRENCE, BOCHAR DANIEL AUSTIN, TRIEVEL RAYMOND C, COLLINS MARGARET LYNN, BARRETT STEPHEN DOUGLAS, JOHNSON JEFFREY KEITH, KEYES GREGORY SCOTT, ENDRES GREGORY WILLIAM, BLAZER LEVI LYNN, SIDHU RANJINDER SINGH
Format: Patent
Sprache:eng
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