HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF

The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and...

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Hauptverfasser: QIU GUANPENG, LU YONGHUA, WANG HERAN, ZHANG ZONGYUAN, YE KANGZHI, GU ZHENG, YUAN MINGYUN, SU GUIZHUAN, WEN JIAPING, CHEN GANG, TANG PENGCHO, KANG PANPAN, WEI YONGGANG, WU WUYONG, ZHU GUOZHI, WANG YINCAI, LAN CHENGSHENG
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creator QIU GUANPENG
LU YONGHUA
WANG HERAN
ZHANG ZONGYUAN
YE KANGZHI
GU ZHENG
YUAN MINGYUN
SU GUIZHUAN
WEN JIAPING
CHEN GANG
TANG PENGCHO
KANG PANPAN
WEI YONGGANG
WU WUYONG
ZHU GUOZHI
WANG YINCAI
LAN CHENGSHENG
description The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF
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