RHO KINASE INHIBITORS
Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compos...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | WU FRANK HICKEY EUGENE RICHARD PROKOPOWICZ ANTHONY S SHIH CHENG-KON BOSANAC TODD YOUNG ERICK RICHARD KIRRANE, JR. THOMAS MARTIN GINN JOHN DAVID LIU WEIMIN SCHLYER SABINE K SNOW ROGER JOHN TURNER MICHAEL ROBERT |
| description | Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2015297581A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2015297581A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2015297581A13</originalsourceid><addsrcrecordid>eNrjZBAN8vBX8Pb0cwx2VfD08_B08gzxDwrmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBoamRpbmphaGjobGxKkCABLAH98</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>RHO KINASE INHIBITORS</title><source>esp@cenet</source><creator>WU FRANK ; HICKEY EUGENE RICHARD ; PROKOPOWICZ ANTHONY S ; SHIH CHENG-KON ; BOSANAC TODD ; YOUNG ERICK RICHARD ; KIRRANE, JR. THOMAS MARTIN ; GINN JOHN DAVID ; LIU WEIMIN ; SCHLYER SABINE K ; SNOW ROGER JOHN ; TURNER MICHAEL ROBERT</creator><creatorcontrib>WU FRANK ; HICKEY EUGENE RICHARD ; PROKOPOWICZ ANTHONY S ; SHIH CHENG-KON ; BOSANAC TODD ; YOUNG ERICK RICHARD ; KIRRANE, JR. THOMAS MARTIN ; GINN JOHN DAVID ; LIU WEIMIN ; SCHLYER SABINE K ; SNOW ROGER JOHN ; TURNER MICHAEL ROBERT</creatorcontrib><description>Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151022&DB=EPODOC&CC=US&NR=2015297581A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151022&DB=EPODOC&CC=US&NR=2015297581A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WU FRANK</creatorcontrib><creatorcontrib>HICKEY EUGENE RICHARD</creatorcontrib><creatorcontrib>PROKOPOWICZ ANTHONY S</creatorcontrib><creatorcontrib>SHIH CHENG-KON</creatorcontrib><creatorcontrib>BOSANAC TODD</creatorcontrib><creatorcontrib>YOUNG ERICK RICHARD</creatorcontrib><creatorcontrib>KIRRANE, JR. THOMAS MARTIN</creatorcontrib><creatorcontrib>GINN JOHN DAVID</creatorcontrib><creatorcontrib>LIU WEIMIN</creatorcontrib><creatorcontrib>SCHLYER SABINE K</creatorcontrib><creatorcontrib>SNOW ROGER JOHN</creatorcontrib><creatorcontrib>TURNER MICHAEL ROBERT</creatorcontrib><title>RHO KINASE INHIBITORS</title><description>Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBAN8vBX8Pb0cwx2VfD08_B08gzxDwrmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBoamRpbmphaGjobGxKkCABLAH98</recordid><startdate>20151022</startdate><enddate>20151022</enddate><creator>WU FRANK</creator><creator>HICKEY EUGENE RICHARD</creator><creator>PROKOPOWICZ ANTHONY S</creator><creator>SHIH CHENG-KON</creator><creator>BOSANAC TODD</creator><creator>YOUNG ERICK RICHARD</creator><creator>KIRRANE, JR. THOMAS MARTIN</creator><creator>GINN JOHN DAVID</creator><creator>LIU WEIMIN</creator><creator>SCHLYER SABINE K</creator><creator>SNOW ROGER JOHN</creator><creator>TURNER MICHAEL ROBERT</creator><scope>EVB</scope></search><sort><creationdate>20151022</creationdate><title>RHO KINASE INHIBITORS</title><author>WU FRANK ; HICKEY EUGENE RICHARD ; PROKOPOWICZ ANTHONY S ; SHIH CHENG-KON ; BOSANAC TODD ; YOUNG ERICK RICHARD ; KIRRANE, JR. THOMAS MARTIN ; GINN JOHN DAVID ; LIU WEIMIN ; SCHLYER SABINE K ; SNOW ROGER JOHN ; TURNER MICHAEL ROBERT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2015297581A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>WU FRANK</creatorcontrib><creatorcontrib>HICKEY EUGENE RICHARD</creatorcontrib><creatorcontrib>PROKOPOWICZ ANTHONY S</creatorcontrib><creatorcontrib>SHIH CHENG-KON</creatorcontrib><creatorcontrib>BOSANAC TODD</creatorcontrib><creatorcontrib>YOUNG ERICK RICHARD</creatorcontrib><creatorcontrib>KIRRANE, JR. THOMAS MARTIN</creatorcontrib><creatorcontrib>GINN JOHN DAVID</creatorcontrib><creatorcontrib>LIU WEIMIN</creatorcontrib><creatorcontrib>SCHLYER SABINE K</creatorcontrib><creatorcontrib>SNOW ROGER JOHN</creatorcontrib><creatorcontrib>TURNER MICHAEL ROBERT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WU FRANK</au><au>HICKEY EUGENE RICHARD</au><au>PROKOPOWICZ ANTHONY S</au><au>SHIH CHENG-KON</au><au>BOSANAC TODD</au><au>YOUNG ERICK RICHARD</au><au>KIRRANE, JR. THOMAS MARTIN</au><au>GINN JOHN DAVID</au><au>LIU WEIMIN</au><au>SCHLYER SABINE K</au><au>SNOW ROGER JOHN</au><au>TURNER MICHAEL ROBERT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RHO KINASE INHIBITORS</title><date>2015-10-22</date><risdate>2015</risdate><abstract>Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US2015297581A1 |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | RHO KINASE INHIBITORS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T16%3A55%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=WU%20FRANK&rft.date=2015-10-22&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2015297581A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |