PHOSPHORYLATED AKT-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING

The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry.

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Bibliographische Detailangaben
Hauptverfasser: NAG ARUNDHATI, HENNING RYAN K, DAS SAMIR, HEATH JAMES R, VARGHESE JOSEPH O
Format: Patent
Sprache:eng
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Zusammenfassung:The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry.