METHOD OF DETERMINING THE FRACTION OF FETAL DNA IN MATERNAL BLOOD USING HLA MARKERS

The invention comprises a method of determining the fraction of fetal DNA in maternal blood or plasma using HLA locus wherein the maternal and fetal HLA alleles are detected and quantified by clonal or digital methods.

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Bibliographische Detailangaben
Hauptverfasser:	RASTROU MELINDA, HOGLUND BRYAN, MOONSAMY PRISCILLA, ERLICH HENRY, TSAN ALISON, NEWTON NICK, SCHOENBRUNNER NANCY, HOLCOMB CHERIE
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention comprises a method of determining the fraction of fetal DNA in maternal blood or plasma using HLA locus wherein the maternal and fetal HLA alleles are detected and quantified by clonal or digital methods.