DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperp...
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| creator | MITCHELL IAN S XU RUI XIAO DENGMING BENCSIK JOSEF R SPENCER KEITH LEE KALLAN NICHOLAS C BLAKE JAMES F |
| description | The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer. |
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HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150709&DB=EPODOC&CC=US&NR=2015191479A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150709&DB=EPODOC&CC=US&NR=2015191479A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MITCHELL IAN S</creatorcontrib><creatorcontrib>XU RUI</creatorcontrib><creatorcontrib>XIAO DENGMING</creatorcontrib><creatorcontrib>BENCSIK JOSEF R</creatorcontrib><creatorcontrib>SPENCER KEITH LEE</creatorcontrib><creatorcontrib>KALLAN NICHOLAS C</creatorcontrib><creatorcontrib>BLAKE JAMES F</creatorcontrib><title>DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS</title><description>The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLBw8fSIdAnydwsN8lcIiAzy9PV08fRzDVZwBCLvEIWAIP8QV08_BW9PP8dgVwVPPw9PJ88Q_6BgHgbWtMSc4lReKM3NoOzmGuLsoZtakB-fWlyQmJyal1oSHxpsZGBoamhpaGJu6WhoTJwqADCnKcg</recordid><startdate>20150709</startdate><enddate>20150709</enddate><creator>MITCHELL IAN S</creator><creator>XU RUI</creator><creator>XIAO DENGMING</creator><creator>BENCSIK JOSEF R</creator><creator>SPENCER KEITH LEE</creator><creator>KALLAN NICHOLAS C</creator><creator>BLAKE JAMES F</creator><scope>EVB</scope></search><sort><creationdate>20150709</creationdate><title>DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS</title><author>MITCHELL IAN S ; 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS |
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