Dry Powder Inhalers with Dual Piercing Members and Methods of Operating Same

A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose...

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Hauptverfasser: THOE GERALD A, LEWIS SCOTT ALEXANDER, TUCKWELL JONATHAN DAVID, SKAKOON JAMES G, SCHUELKE DAVID A, HARRIS DAVID, RUCKDESCHEL THOMAS W, GOW ANDREW MURRAY
Format: Patent
Sprache:eng
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Zusammenfassung:A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.