IRE-1alpha INHIBITORS

Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agent...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	WADE WARREN STANFIELD, YANG YUN, PATTERSON JOHN BRUCE, WU ZHIPENG, ZENG QINGPING, TORO ANDRAS, ZUBOVICS ZOLTAN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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