Assays for resistance to echinocandin-class drugs

Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, p...

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Hauptverfasser: KELLY ROSEMARIE, KAHN JENNIFER N, DOUGLAS CAMERON M, PARK STEVEN, PERLIN DAVID S, PARENT STEPHEN A
Format: Patent
Sprache:eng
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