Antibodies That Bind Peptidoglycan Recognition Protein 1

Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TRE...

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Hauptverfasser: STENNICKE VIBEKE WESTPHAL, HEIPEL MARK, HJORTH SIV ANNEGRETHE, READ CHRISTINE BRENDER, TANG XIAOTING, KUIJPER JOE
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creator STENNICKE VIBEKE WESTPHAL
HEIPEL MARK
HJORTH SIV ANNEGRETHE
READ CHRISTINE BRENDER
TANG XIAOTING
KUIJPER JOE
description Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title Antibodies That Bind Peptidoglycan Recognition Protein 1
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