METHODS OF ENHANCING PROTEIN QUALITY AND QUANTITY BY YEAST FED-BATCH FERMENTATION

The present invention describes a method for producing an antibody in Pichia pastoris, such as by fed-batch fermentation. The method may include a strategy of increasing the ethanol concentration to 18-22 g/L and then maintaining the ethanol level at 5-17 g/L to stabilize the cell mass and enhance t...

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Bibliographische Detailangaben
Hauptverfasser: EAGAN BRUCE E, XING ZIZHUO, XU XUANKUO, YOU LI, CAMPBELL GEORGE S, QIAN NAN-XIN, QIAN YUEMING, LI ZHENGJIAN
Format: Patent
Sprache:eng
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