SUBSTITUTED HYDOXAMIC ACIDS AND USES THEREOF

SUBSTITUTED HYDOXAMIC ACIDS AND USES THEREOF

This invention provides compounds of formula (I): wherein R1, R1b, R2a, R2b, R2c, and R2d have values as described in the specification, useful as inhibitors of HDAC6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositi...

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Hauptverfasser: GOULD ALEXANDRA E, HARRISON SEAN J, XU HE, CALDERWOOD EMILY F, BLACKBURN CHRISTOPHER, GIGSTAD KENNETH M
Format: Patent
Sprache:eng
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator GOULD ALEXANDRA E
HARRISON SEAN J
XU HE
CALDERWOOD EMILY F
BLACKBURN CHRISTOPHER
GIGSTAD KENNETH M
description This invention provides compounds of formula (I): wherein R1, R1b, R2a, R2b, R2c, and R2d have values as described in the specification, useful as inhibitors of HDAC6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title SUBSTITUTED HYDOXAMIC ACIDS AND USES THEREOF
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