TETRACYCLIC COMPOUNDS

TETRACYCLIC COMPOUNDS

This disclosure relates to new tetracyclic compounds that may be used to modulate a histamine receptor in an individual. The compounds in one embodiment are tetracyclic[4,3-b]indoles. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a v...

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Bibliographische Detailangaben
Hauptverfasser: GRIGORIEV VLADIMIR VIKTOROVICH, SHEVTSOVA ELENA FEOFANOVNA, DUGAR SUNDEEP, BACHURIN SERGEY OLEGOVICH, JAIN RAJENDRA PARASMAL, CHAKRAVARTY SARVAJIT, PROTTER ANDREW ASHER, HUNG DAVID T, BEZNOSKO BOGDAN KONSTANTINOVICH, USTINOV ANATOLY KONSTANTINOVICH
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This disclosure relates to new tetracyclic compounds that may be used to modulate a histamine receptor in an individual. The compounds in one embodiment are tetracyclic[4,3-b]indoles. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.