METHODS AND MEANS FOR TREATMENT OF OSTEOARTHRITIS

The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VANDEGHINSTE NICK, MA LIBIN, MILLE-BAKER BLANDINE, MICHIELS FRITS, TOMME PETER HERWIG MARIA, VAN ES HELMUTH H.G
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean cartilage thickness in a subject.