Cytotoxicity Mediation of Cells Evidencing Surface Expression of CD44

This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optio...

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Hauptverfasser: YOUNG DAVID S.F, FAN SHEUNG TAT, LEE TERENCE KIN WAH, SAYEGH DAAD, POON RONNIE TUNG PING
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creator YOUNG DAVID S.F
FAN SHEUNG TAT
LEE TERENCE KIN WAH
SAYEGH DAAD
POON RONNIE TUNG PING
description This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. The invention further relates to binding assays which utilize the CDMAB of the instant invention.
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subjects CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
title Cytotoxicity Mediation of Cells Evidencing Surface Expression of CD44
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