Cytotoxicity Mediation of Cells Evidencing Surface Expression of CD44
This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optio...
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creator | YOUNG DAVID S.F FAN SHEUNG TAT LEE TERENCE KIN WAH SAYEGH DAAD POON RONNIE TUNG PING |
description | This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. The invention further relates to binding assays which utilize the CDMAB of the instant invention. |
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The invention further relates to binding assays which utilize the CDMAB of the instant invention.</description><language>eng</language><subject>CHEMISTRY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; TESTING</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20131128&DB=EPODOC&CC=US&NR=2013315896A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20131128&DB=EPODOC&CC=US&NR=2013315896A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YOUNG DAVID S.F</creatorcontrib><creatorcontrib>FAN SHEUNG TAT</creatorcontrib><creatorcontrib>LEE TERENCE KIN WAH</creatorcontrib><creatorcontrib>SAYEGH DAAD</creatorcontrib><creatorcontrib>POON RONNIE TUNG PING</creatorcontrib><title>Cytotoxicity Mediation of Cells Evidencing Surface Expression of CD44</title><description>This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. The invention further relates to binding assays which utilize the CDMAB of the instant invention.</description><subject>CHEMISTRY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHB1rizJL8mvyEzOLKlU8E1NyUwsyczPU8hPU3BOzckpVnAty0xJzUvOzEtXCC4tSktMTlVwrSgoSi0uhilzMTHhYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQVAXXmpJfGhwUYGhsbGhqYWlmaOhsbEqQIAfq8zYw</recordid><startdate>20131128</startdate><enddate>20131128</enddate><creator>YOUNG DAVID S.F</creator><creator>FAN SHEUNG TAT</creator><creator>LEE TERENCE KIN WAH</creator><creator>SAYEGH DAAD</creator><creator>POON RONNIE TUNG PING</creator><scope>EVB</scope></search><sort><creationdate>20131128</creationdate><title>Cytotoxicity Mediation of Cells Evidencing Surface Expression of CD44</title><author>YOUNG DAVID S.F ; FAN SHEUNG TAT ; LEE TERENCE KIN WAH ; SAYEGH DAAD ; POON RONNIE TUNG PING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2013315896A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2013</creationdate><topic>CHEMISTRY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>YOUNG DAVID S.F</creatorcontrib><creatorcontrib>FAN SHEUNG TAT</creatorcontrib><creatorcontrib>LEE TERENCE KIN WAH</creatorcontrib><creatorcontrib>SAYEGH DAAD</creatorcontrib><creatorcontrib>POON RONNIE TUNG PING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YOUNG DAVID S.F</au><au>FAN SHEUNG TAT</au><au>LEE TERENCE KIN WAH</au><au>SAYEGH DAAD</au><au>POON RONNIE TUNG PING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Cytotoxicity Mediation of Cells Evidencing Surface Expression of CD44</title><date>2013-11-28</date><risdate>2013</risdate><abstract>This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. 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subjects | CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS TESTING |
title | Cytotoxicity Mediation of Cells Evidencing Surface Expression of CD44 |
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