Phenyl-Heteroaryl Derivatives and Methods of Use Thereof

Phenyl-Heteroaryl Derivatives and Methods of Use Thereof

The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of co...

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Hauptverfasser: BONDLELA MURALIDHAR, SUNDERMANN KURT, ZHU JEFF J, RAO MOHAN, ANDREWS ROBERT C, JONES DAVID, BANNER WILLIAM K, WANG PINGZHEN, COOPER JEREMY T, QABAJA GHASSAN, GOWDA RAJU B, GUPTA SUPARNA, GOHIMUKKULA DEVI R, HARI ANITHA
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator BONDLELA MURALIDHAR
SUNDERMANN KURT
ZHU JEFF J
RAO MOHAN
ANDREWS ROBERT C
JONES DAVID
BANNER WILLIAM K
WANG PINGZHEN
COOPER JEREMY T
QABAJA GHASSAN
GOWDA RAJU B
GUPTA SUPARNA
GOHIMUKKULA DEVI R
HARI ANITHA
description The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the use of such compounds and/or pharmaceutical compositions in treating RAGE-mediated diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Phenyl-Heteroaryl Derivatives and Methods of Use Thereof
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