STABLE POWDER FORMULATION CONTAINING AN ANTICHOLINGERIC AGENT

STABLE POWDER FORMULATION CONTAINING AN ANTICHOLINGERIC AGENT

The invention relates to a spray-dried powder formulation comprising particles that contain the following components i) to iii): i) anticholinergic agents, in particular at least one compound of formula 1, in which X- represents a negatively charged anion, ii) at least one embedding material selecte...

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Hauptverfasser: WEILER CLAUDIUS, PIEROTH WERNER, TRUNK MICHAEL
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator WEILER CLAUDIUS
PIEROTH WERNER
TRUNK MICHAEL
description The invention relates to a spray-dried powder formulation comprising particles that contain the following components i) to iii): i) anticholinergic agents, in particular at least one compound of formula 1, in which X- represents a negatively charged anion, ii) at least one embedding material selected from the group consisting of mono- or disaccharides, oligosaccharides, polymers, sugar alcohols and cholesterol, iii) an organic, physiologically acceptable, sterically demanding acid, selected from the group consisting of ascorbic acid, a monovalent, divalent or trivalent carboxylic acid, with the exception of amino carboxylic acids, preferably fumaric acid, oxalic acid, or diacetic acid, and a fruit acid or culinary acid, preferably citric acid, tartaric acid, malic acid, lactic acid, acetic acid, alpha-hydroxycaprylic acid or gluconic acid. The invention also relates to a method for producing said formulation.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title STABLE POWDER FORMULATION CONTAINING AN ANTICHOLINGERIC AGENT
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