PROTEASE-ACTIVATABLE PORE-FORMING POLYPEPTIDES

An isolated pore-forming polypeptide is disclosed which comprises a naturally-occurring plugging module and a naturally-occurring pore domain, wherein at least one amino acid of the pore-forming polypeptide is mutated to generate a protease cleavage site, serving to at least partially remove the plu...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	NIR URI, BEN-DAVID BARAK, PAAS YOAV, PITTEL ILYA
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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